Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension

Christophe Guignabert, Carole Phan, Andrei Seferian, +16

Journal of Clinical Investigation

Dasatinib-induced PahDasatinib TreatmentImmunologyPathologyCell Death +15

C-Kit–Positive Cells Accumulate in Remodeled Vessels of Idiopathic Pulmonary Arterial Hypertension

David Montani, Frédéric Perros, Natalia Gambaryan, +10

American Journal of Respiratory and Critical Care Medicine

Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension

Nicolas Ricard, Ly Tu, Morane Le Hiress, +10

Circulation

Circulating haemopoietic and endothelial progenitor cells are decreased in COPD

Paolo Palange, Ugo Testa, Alice Huertas, +8

European Respiratory Journal

InflammationEndothelial Progenitor CellsPulmonary CirculationAdvanced Lung DiseaseLung Inflammation +13

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

Morane Le Hiress, Ly Tu, Nicolas Ricard, +9

American Journal of Respiratory and Critical Care Medicine

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

Yuichi Tamura, Carole Phan, Ly Tu, +8

Journal of Clinical Investigation

HypertensionLung InflammationImmunologyCell DeathPulmonary Hypertension +17

Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

Ly Tu, Agnès Desroches‐Castan, Christine Mallet, +14

Circulation Research

Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension

Alice Huertas, Ly Tu, Natalia Gambaryan, +9

European Respiratory Journal

HypertensionSerum LeptinImmunologyPulmonary HypertensionImmune Dysregulation +14

Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels

David J. Rowlands, Mohammad Naimul Islam, Shonit Das, +9

Journal of Clinical Investigation

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyRenal Inflammation +22

A Critical Role for p130 ^Cas in the Progression of Pulmonary Hypertension in Humans and Rodents

Ly Tu, Frances S. de Man, Barbara Girerd, +11

American Journal of Respiratory and Critical Care Medicine