Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex - Concepedia

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Publication | Open Access

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

DOI Full Paper Access

187

Citations

35

References

2015

Year

Morane Le Hiress, Ly Tu, Nicolas Ricard, Carole Phan, Raphaël Thuillet, Élie Fadel, Peter Dorfmüller, David Montani, Frances S. de Man, Marc Humbert,

American Journal of Respiratory and Critical Care Medicine

Abstract

We report here that CD74 and MIF are markedly increased and activated in patients with iPAH, contributing to the abnormal proinflammatory phenotype of pulmonary ECs in iPAH.

References

	Year	Citations

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