Nuclease Activity of the Human SAMHD1 Protein Implicated in the Aicardi-Goutières Syndrome and HIV-1 Restriction

Natalia Beloglazova, Robert Flick, Anatoli Tchigvintsev, +4

Journal of Biological Chemistry

Viral ReplicationImmunologyMolecular BiologyViral Structural ProteinNuclease Activity +16

Determinants and Prediction of Esterase Substrate Promiscuity Patterns

Mónica Martínez‐Martínez, Cristina Coscolín, Gerard Santiago, +40

ACS Chemical Biology

BiosynthesisBioorganic ChemistryEngineeringBiochemistryNatural Sciences +13

The environment shapes microbial enzymes: five cold-active and salt-resistant carboxylesterases from marine metagenomes

Anatoli Tchigvintsev, Hai Tran, Ana Popovic, +15

Applied Microbiology and Biotechnology

BiologyMarine MetagenomesBioenergeticsExtremophileMicrobial Physiology +6

Screening and Characterization of Novel Polyesterases from Environmental Metagenomes with High Hydrolytic Activity against Synthetic Polyesters

Mahbod Hajighasemi, Anatoli Tchigvintsev, B. Nocek, +18

Environmental Science & Technology

Environmental MetagenomesEngineeringBioplasticSynthetic PolyestersEnzymatic Modification +18

Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

Ana Popovic, Hai Tran, Anatoly Tchigvintsev, +18

Scientific Reports

Molecular DiversityCellular EnzymologyBiochemistryBiomolecular ToolNatural Sciences +13

Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids

Anna N. Khusnutdinova, Robert Flick, Ana Popovic, +7

Biotechnology Journal

Adipic AcidAldo-keto ReductaseRedox BiologyBiosynthesisBioenergetics +15

Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from <i>Sulfolobus solfataricus</i>

Sofia Lemak, Natalia Beloglazova, B. Nocek, +7

Journal of the American Chemical Society

Protein FoldingNatural SciencesMolecular BiologyGenetic EngineeringDna Replication +12

Micronutrient supplements can promote disruptive protozoan and fungal communities in the developing infant gut

Ana Popovic, Céline Bourdon, Pauline W. Wang, +6

Nature Communications

Identification and Characterization of Carboxyl Esterases of Gill Chamber-Associated Microbiota in the Deep-Sea Shrimp Rimicaris exoculata by Using Functional Metagenomics

María M. Alcaide, Anatoli Tchigvintsev, Mónica Martínez‐Martínez, +14

Applied and Environmental Microbiology

EngineeringCarboxyl EsterasesR. Exoculata GillShrimp Rimicaris ExoculataMicrobial Ecology +14

Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides

Anatoli Tchigvintsev, Dmitri Tchigvintsev, Robert Flick, +16

Chemistry & Biology

Cell Division ArrestProtein FunctionCellular EnzymologyBiochemistryNatural Sciences +10