Laurence T. Plante

Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex.

David A. Matthews, Richard A. Alden, J.T. Bolin et al. · Journal of Biological Chemistry · 1978 · 225 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Inhibition of thymidylate synthetase and dihydrofolate reductase by naturally occurring oligoglutamate derivatives of folic acid.

Morris Friedkin, Laurence T. Plante, Elizabeth J. Crawford et al. · Journal of Biological Chemistry · 1975 · 59 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +8

Tetrahydrohomofolate, a Specific Inhibitor of Thymidylate Synthetase

Leon Goodman, Roy L. Kisliuk, Edward J. Pastore et al. · Journal of the American Chemical Society · 1964 · 51 citations

Natural Sciences, Chemistry, Pharmacology +10

Enzyme Studies with New Analogues of Folic Acid and Homofolic Acid

Laurence T. Plante, Elizabeth J. Crawford, Morris Friedkin · Journal of Biological Chemistry · 1967 · 46 citations · Full text

Life Sciences, Biochemistry, Enzymology +11

Diastereoisomers of 5,10-methylene-5,6,7,8-tetrahydropteroyl-D-glutamic acid

Roy L. Kisliuk, Dan Strumpf, Y. Gaumont et al. · Journal of Medicinal Chemistry · 1977 · 33 citations

Pharmacy, Chemistry, Medicinal Chemistry +5