PK-sensitive PrPSc Is Infectious and Shares Basic Structural Features with PK-resistant PrPSc

Gustavo Sajnani, Christopher J. Silva, Adriana Ramos, +9

PLoS Pathogens

Mass spectrometric detection of attomole amounts of the prion protein by nanoLC/MS/MS

Bruce Onisko, Irina Dynin, Jesús R. Requena, +3

Journal of the American Society for Mass Spectrometry

Creutzfeldt-jakob DiseaseBiological Mass SpectrometryVveqmcttqyqk MethodSensitive QuantitationProteomic Technology +21

Human and rat brain lipofuscin proteome

Philipp Ottis, Katharina Koppe, Bruce Onisko, +7

PROTEOMICS

NeuropeptidesCell DeathOxidative StressAutophagyDegenerative Pathology +16

Scrapie Prion Protein Structural Constraints Obtained by Limited Proteolysis and Mass Spectrometry

Gustavo Sajnani, Miguel A. Pastrana, Irina Dynin, +2

Journal of Molecular Biology

BiochemistryProtein FoldingMedicineNatural SciencesMass Spectrometry +6

Structural Organization of Mammalian Prions as Probed by Limited Proteolysis

Ester Vázquez-Fernández, Jana Alonso, Miguel A. Pastrana, +7

PLoS ONE

Protein AssemblyBiochemistryProtein FoldingNatural SciencesMedicine +9

Assessing the Role of Oxidized Methionine at Position 213 in the Formation of Prions in Hamsters

Christopher J. Silva, Bruce Onisko, Irina Dynin, +5

Biochemistry

Utility of Mass Spectrometry in the Diagnosis of Prion Diseases

Christopher J. Silva, Bruce Onisko, Irina Dynin, +3

Analytical Chemistry

Creutzfeldt-jakob DiseaseMammalian SpeciesBiological Mass SpectrometryPathologyLaboratory Animal Study +16

Oxidation of Methionine 216 in Sheep and Elk Prion Protein Is Highly Dependent upon the Amino Acid at Position 218 but Is Not Important for Prion Propagation

Christopher J. Silva, Irina Dynin, Melissa L. Erickson‐Beltran, +5

Biochemistry

Biological Mass SpectrometryMolecular BiologyMethionine 216Prion FormationRedox Biology +22

Sensitive, preclinical detection of prions in brain by nanospray liquid chromatography/tandem mass spectrometry

Bruce Onisko, Christopher J. Silva, Irina Dynin, +5

Rapid Communications in Mass Spectrometry

Creutzfeldt-jakob DiseaseBiological Mass SpectrometryPrp 27-30Neurophysiological BiomarkersNeurochemical Biomarkers +18

Safe and Effective Means of Detecting and Quantitating Shiga-Like Toxins in Attomole Amounts

Christopher J. Silva, Melissa L. Erickson‐Beltran, Craig Skinner, +5

Analytical Chemistry