CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

Kyuho Han, Sarah E. Pierce, Amy Li, +22

Nature

Crispr ScreensGene EditingGenome EditingMedicineCell Biology +2

A genome-wide atlas of co-essential modules assigns function to uncharacterized genes

Michael Wainberg, Roarke A. Kamber, Akshay Balsubramani, +14

Nature Genetics

BiologyBioinformaticsGenome-wide AtlasCo-essential ModulesGenome Study +13

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Michael S. Haney, Christopher J. Bohlen, David W. Morgens, +24

Nature Genetics

Phagocytosis RegulatorsGenetic EngineeringGene EditingGenome EditingMedicine +2

Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis

Roarke A. Kamber, Yoko Nishiga, Bhek Morton, +15

Nature

Tumor BiologyInter-cellular Crispr ScreensCancer Cell BiologyGene EditingGenome Editing +4

Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras

Green Ahn, Nicholas M. Riley, Roarke A. Kamber, +5

Science

Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase

Roarke A. Kamber, Christopher J. Shoemaker, Vladimir Denic

Molecular Cell

Cell AutophagyMitophagySignal TransductionSignaling PathwayAtg1 Kinase +10

The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane

N. Weir, Roarke A. Kamber, James S Martenson, +1

eLife

Protein SecretionProtein AssemblyMolecular BiologyCytoskeletonMsp1-dependent Turnover +21

Mapping Loci Associated With Tail Color and Sex Determination in the Short-Lived Fish <i>Nothobranchius furzeri</i>

Dario Riccardo Valenzano, Jeanette Kirschner, Roarke A. Kamber, +7

Genetics

A pathway of targeted autophagy is induced by DNA damage in budding yeast

Vinay V. Eapen, David P. Waterman, Amélie Bernard, +13

Proceedings of the National Academy of Sciences

Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes

Ying Chen, Gregory B. Craven, Roarke A. Kamber, +5

Nature Chemistry

EngineeringBiochemistryLigandable TyrosinesDirect MappingFluorous Synthesis +6