Ryan Lupo

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism

Douglas B. Fox, Nina Marie G. Garcia, Brock J. McKinney et al. · Nature Metabolism · 2020 · 199 citations

Reductive Stress, Tumor Biology, Redox Regulator +12

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors

Andrea Walens, Ashley V. DiMarco, Ryan Lupo et al. · eLife · 2019 · 194 citations · Full text

Breast Oncology, Immunology, Immune Regulation +18

Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer

Nathaniel W. Mabe, Douglas B. Fox, Ryan Lupo et al. · Journal of Clinical Investigation · 2018 · 51 citations · Full text

Epigenetic Silencing, Breast Cancer Recurrence, Breast Oncology +14

Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence

Andrea Walens, Jiaxing Lin, Jeffrey S. Damrauer et al. · Nature Communications · 2020 · 46 citations · Full text

G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

Nathaniel W. Mabe, Nina Marie G. Garcia, Shayna E. Wolery et al. · Cell Reports · 2020 · 37 citations · Full text