Interleukin 1 and tumor necrosis factor synergistically stimulate prostaglandin synthesis and phospholipase A2 release from rat renal mesangial cells

Josef Pfeilschifter, W. Pignat, Klaus Vosbeck, +1

Biochemical and Biophysical Research Communications

InflammationCytokineTumor Necrosis FactorUrologyAnti-inflammatory +13

Evaluation of the<i>in Vivo</i>and<i>in Vitro</i>Calcium Regulating Actions of Noncalcitonin Peptides Produced via Calcitonin Gene Expression*

Bernard A. Roos, Jan A. Fischer, W. Pignat, +2

Endocrinology

Cyclic AMP mimics, but does not mediate, interleukin-1- and tumour-necrosis-factor-stimulated phospholipase A2 secretion from rat renal mesangial cells

Josef Pfeilschifter, J Leighton, W. Pignat, +2

Biochemical Journal

Specific activation of the nuclear receptors PPARgamma and RORA by the antidiabetic thiazolidinedione BRL 49653 and the antiarthritic thiazolidinedione derivative CGP 52608.

Irmgard Wiesenberg, Michele Chiesi, Martin Missbach, +3

PubMed

Molecular PharmacologyAnti-inflammatoryBiochemistryMedicineLipid Peroxidation +11

Release of phospholipase A₂ activity from rat vascular smooth muscle cells mediated by cAMP

Josef Pfeilschifter, W. Pignat, F. Märki, +1

European Journal of Biochemistry

Rat AortaCellular PharmacologyExperimental PharmacologyCulture MediumCellular Physiology +16

PDGF suppresses the activation of group II phospholipase A₂gene expression by interleukin I and forskolin in mesangial cells

Heiko Mühl, Thomas Geiger, W. Pignat, +4

FEBS Letters

Transforming growth factors type‐β and dexamethasone attenuate group II phospholipase A₂ gene expression by interleukin‐1 and forskolin in rat mesangial cells

Heiko Mühl, Thomas Geiger, W. Pignat, +7

FEBS Letters

Transforming growth factor <i>β</i>2 differentially modulates interleukin-1 <i>β</i>- and tumour-necrosis-factor-<i>α</i>-stimulated phospholipase A2 and prostaglandin E2 synthesis in rat renal mesangial cells

Josef Pfeilschifter, W. Pignat, J Leighton, +3

Biochemical Journal

Pyrrolidine dithiocarbamate differentially affects cytokine‐ and cAMP‐induced expression of group II phospholipase A₂ in rat renal mesangial cells

Gaby Walker, Dieter Kunz, W. Pignat, +2

FEBS Letters

Cytokine regulation of Group II phospholipase A2 expression in glomerular mesangial cells

Josef Pfeilschifter, Heiko Mühl, W. Pignat, +2

European Journal of Clinical Pharmacology

InflammationRenal FunctionSignal TransductionCytokine RegulationCell Signaling +9