Frédérique Klupsch

Comparative pharmacological studies of melatonin receptors: mt1, mt2 and mt3/qr2. tissue distribution of mt3/qr2 11Abbreviations: MCA-NAT, methoxy-carbonylamino-N-acetyltrypta- mine, 2-[125I]-I-MCA-NAT, 2-[125I]-iodomethoxy-carbonylamino-N-acetyltryptamine; 2-IbMT, 2-iodo-N-butanoyl-5-methoxytryptamine; 4-P-PDOT, 4-phenyl-2-propionamido-tetraline; DH97, N-pentanoyl-2-benzyltryptamine; S20760, 5-methoxy-N-cyclopropanoyl-tryptamine; S24635, N-[2-(5-carbamoylbenzofuran-3-yl)ethyl]-acetamide; S25726, N-methyl-(3-{2-[(cyclopropylcarbonyl)-amino]ethyl}benzo[b]furan-5-yl)carbamate; S26553, N-methyl-{1-[2-(acetylamino)ethyl]-naphthalen-7-yl}carbamate.

Olivier Nosjean, Jean‐Paul Nicolas, Frédérique Klupsch et al. · Biochemical Pharmacology · 2001 · 187 citations

New benzo[5,6]pyrrolizino[1,2- b ]quinolines as cytotoxic agents

Aurore Perzyna, Frédérique Klupsch, Raymond Houssin et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 42 citations

Medicinal Chemistry, New Benzo, Biochemistry +6

2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers

Jamal El Bakali, Frédérique Klupsch, Aurore Guédin et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 27 citations

Telomeric G-quadruplex Stabilizers, Heterocyclic, Heterocycle Chemistry

Conformational Restriction Leading to a Selective CB₂ Cannabinoid Receptor Agonist Orally Active Against Colitis

Jamal El Bakali, Giulio G. Muccioli, Mathilde Body–Malapel et al. · ACS Medicinal Chemistry Letters · 2014 · 26 citations · Full text

-One Scaffold, Gastrointestinal Pharmacology, Immunology +19

Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction

Raphaël Le Biannic, Romain Magnez, Frédérique Klupsch et al. · European Journal of Medicinal Chemistry · 2022 · 25 citations · Full text

Immune Checkpoint, Medicine, Immunology +7