Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34 + Hematopoietic Stem and Progenitor Cells

Kai-Hsin Chang, Sarah E. Smith, Timothy M. Sullivan, +17

Molecular Therapy — Methods & Clinical Development

Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab

Neung‐Seon Seo, Alla Polozova, Mingxuan Zhang, +7

mAbs

Abp 215ImmunologyPathologyStructural SimilarityMolecular Pharmacology +16

Integration of histopathological images and multi-dimensional omics analyses predicts molecular features and prognosis in high-grade serous ovarian cancer

Hao Zeng, Linyan Chen, Mingxuan Zhang, +2

Gynecologic Oncology

Tumor BiologyMulti-dimensional OmicsCancer DetectionMedicineMulti-omics Study +10

Manufacturing process used to produce long-acting recombinant factor VIII Fc fusion protein

Justin T. McCue, Rashmi Kshirsagar, Keith Selvitelli, +8

Biologicals

PM2.5 induces mitochondrial dysfunction via AHR-mediated cyp1a1 overexpression during zebrafish heart development

Jin Chen, Mingxuan Zhang, Hongmei Zou, +3

Toxicology

Ahr-mediated Cyp1a1 OverexpressionMolecular PhysiologyMitochondrial BiogenesisMitochondrial FunctionMitochondrial Dysfunction +6

Fine particulate matter induces heart defects via AHR/ROS-mediated endoplasmic reticulum stress

Mingxuan Zhang, Jin Chen, Yan Jiang, +1

Chemosphere

CardiomyopathyHeart FailurePhysiologyReactive Oxygen SpecieMedicine +4

AHR/cyp1b1 signaling-mediated extrinsic apoptosis contributes to 6PPDQ-induced cardiac dysfunction in zebrafish embryos

Yan Jiang, Mingxuan Zhang, Jinhao Li, +2

Environmental Pollution

6Ppdq-induced Cardiac DysfunctionCardiac MuscleCardiomyopathyHeart FailureDevelopmental Biology +10

Application of Affinity Selection-Mass Spectrometry Assays to Purification and Affinity-Based Screening of the Chemokine Receptor CXCR4

Charles E. Whitehurst, Zhiping Yao, Denise Murphy, +10

Combinatorial Chemistry & High Throughput Screening

New LigandsDrug TargetChemokine BiologyImmunologyBiological Mass Spectrometry +23

AHR-mediated DNA damage contributes to BaP-induced cardiac malformations in zebrafish

Hongmei Zou, Mingxuan Zhang, Stanley Aniagu, +2

The Science of The Total Environment

CardiomyopathyDevelopmental BiologyGeneticsMolecular GeneticsBap-induced Cardiac Malformations +4

Existence of a Noncanonical State of Iron-Bound Transferrin at Endosomal pH Revealed by Hydrogen Exchange and Mass Spectrometry

Cedric E. Bobst, Mingxuan Zhang, Igor A. Kaltashov

Journal of Molecular Biology

BiochemistryNatural SciencesEndosomal PhProton TransferMass Spectrometry +9