Polycomb Protein EZH2 Regulates Tumor Invasion via the Transcriptional Repression of the Metastasis Suppressor RKIP in Breast and Prostate Cancer

Gang Ren, Stavroula Baritaki, Himangi Marathe, +13

Cancer Research

Histone ModificationsEpigenetic ChangeCancer BiologyEpigeneticsTranscriptional Repression +18

RKIP downregulates B-Raf kinase activity in melanoma cancer cells

Sungdae Park, Miranda Yeung, Sandy Beach, +2

Oncogene

Cancer ResearchReceptor Tyrosine KinaseMelanomaMelanoma Cancer CellsTumor Suppressor +4

CRISPR-Cas9 Gene Editing in Lizards through Microinjection of Unfertilized Oocytes

Ashley M. Rasys, Sungdae Park, Rebecca Ball, +3

Cell Reports

BiologyCrispr-cas9-mediated Gene EditingCrispr-cas9 Gene EditingDevelopmental BiologyGenetics +13

Molecular shifts in limb identity underlie development of feathered feet in two domestic avian species

Eric T. Domyan, Zev Kronenberg, Carlos R. Infante, +11

eLife

Domestic Avian SpeciesOrgan FateGeneticsMolecular GeneticsFoot Feathers +19

RKIP inhibits NF‐κB in cancer cells by regulating upstream signaling components of the IκB kinase complex

Huihui Tang, Sungdae Park, Shao‐Cong Sun, +4

FEBS Letters

Shared Enhancer Activity in the Limbs and Phallus and Functional Divergence of a Limb-Genital cis-Regulatory Element in Snakes

Carlos R. Infante, Alexandra G. Mihala, Sungdae Park, +4

Developmental Cell

BiologyFunctional DivergenceDevelopmental BiologyEnhancer ActivityGenetics +7

Two‐component signaling in the AAA+ ATPase DctD: binding Mg ²⁺ and BeF ₃ selects between alternative dimeric states of the receiver domain

Sungdae Park, Matthew Meyer, A. Daniel Jones, +3

The FASEB Journal

Pitx1 broadly associates with limb enhancers and is enriched on hindlimb cis-regulatory elements

Carlos R. Infante, Sungdae Park, Alexandra G. Mihala, +2

Developmental Biology

Transcriptional RegulationDevelopmental BiologyFunctional GenomicsHindlimb Cis-regulatory ElementsGenetics +8

Regulation of RKIP binding to the N‐region of the Raf‐1 kinase

Sungdae Park, Oliver Rath, Sandy Beach, +5

FEBS Letters

The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK

Oliver Rath, Sungdae Park, Huihui Tang, +7

Cellular Signalling

Signal TransductionPocket BindsSignaling PathwayCell RegulationNatural Sciences +8