Roxann Freeman

t-PA–specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes

Be׳eri Niego, Roxann Freeman, Till B. Puschmann et al. · Blood · 2012 · 98 citations · Full text

Synaptic Transmission, Blood-brain Barrier Permeability, Synaptic Signaling +31

The tissue-type plasminogen activator–plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans

Maithili Sashindranath, E. S. G. Sales, Maria Daglas et al. · Brain · 2012 · 87 citations · Full text

Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin

Rachael J. Borg, André L. Samson, Amanda E. Au et al. · PLoS ONE · 2015 · 56 citations · Full text

t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions

Roxann Freeman, Be׳eri Niego, David R. Croucher et al. · Brain Research · 2014 · 24 citations

Cerebral Vascular Regulation, Blood-brain Barrier Model, Blood–brain Barrier +15