Frank Haunert

Proof of Principle in the Selective Treatment of Cancer by Antibody-Directed Enzyme Prodrug Therapy: The Development of a Highly Potent Prodrug This work was supported by the Deutsche Forschungsgemeinschaft (SFB 416) and by the Fonds der Chemischen Industrie.

Lutz F. Tietze, Tim Feuerstein, Anja Fecher et al. · Angewandte Chemie International Edition · 2002 · 55 citations

Immunology, Pharmacotherapy, Immunotherapy +18

A strategy for tumor-selective chemotherapy by enzymatic liberation of seco-duocarmycin SA-derivatives from nontoxic prodrugs

Lutz F. Tietze, Monika Lieb, Tobias Herzig et al. · Bioorganic & Medicinal Chemistry · 2001 · 42 citations

Medicinal Chemistry, Pharmaceutical Science, Seco-duocarmycin Sa-derivatives +9

Clean three-step synthesis of 4,5-dihydro-1H-pyrazoles starting from alcohols using polymer supported reagents

Frank Haunert, Martin H. Bolli, Berthold Hinzen et al. · Journal of the Chemical Society Perkin Transactions 1 · 1998 · 36 citations

Engineering, Mild Oxidation, Clean Synthesis +10

Highly Selective Glycosylated Prodrugs of Cytostatic CC-1065 Analogues for Antibody-Directed Enzyme Tumor Therapy

Lutz F. Tietze, Tobias Herzig, Anja Fecher et al. · ChemBioChem · 2001 · 36 citations

Pharmaceutical Science, Glycobiology, Selective Glycosylated Prodrugs +16

A Concise and Efficient Synthesis of <i>seco</i>‐Duocarmycin SA

Lutz F. Tietze, Frank Haunert, Tim Feuerstein et al. · European Journal of Organic Chemistry · 2003 · 32 citations

Diversity Oriented Synthesis, Biosynthesis, Bioorganic Chemistry +13