Mary Zoeckler

Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole

Haiyan Huang, H Wang, Michael Sinz et al. · Oncogene · 2006 · 209 citations

Medicine, Pharmacokinetics, Pharmacology +9

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

Samuel W. Gerritz, Christopher Cianci, Sean Kim et al. · Proceedings of the National Academy of Sciences · 2011 · 137 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Mark D. Wittman, Joan M. Carboni, Ricardo M. Attar et al. · Journal of Medicinal Chemistry · 2005 · 135 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Fluorine Substitution Can Block CYP3A4 Metabolism-Dependent Inhibition:  Identification of (<i>S</i>)<i>-N</i>-[1-(4-Fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an Orally Bioavailable KCNQ2 Opener Devoid of CYP3A4 Metabolism-Dependent Inhibition

Yong‐Jin Wu, Carl D. Davis, Steven I. Dworetzky et al. · Journal of Medicinal Chemistry · 2003 · 58 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +11

Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates.

Pamela A. Trail, David Willner, Jay O. Knipe et al. · PubMed · 1997 · 56 citations

Medicine, Oncology, Pharmacology +17