Pranathi M. Krishnamurthy

Targeting the MLL complex in castration-resistant prostate cancer

Rohit Malik, Amjad Khan, Irfan A. Asangani et al. · Nature Medicine · 2015 · 216 citations · Full text

Medicine, Oncology, Urology +12

BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer

Irfan A. Asangani, Kari Wilder-Romans, Vijaya L. Dommeti et al. · Molecular Cancer Research · 2016 · 158 citations · Full text

Medicine, Oncology, Pharmacology +17

KRAS Protein Stability Is Regulated through SMURF2: UBCH5 Complex-Mediated β-TrCP1 Degradation

Shirish Shukla, Uday Sankar Allam, Aarif Ahsan et al. · Neoplasia · 2014 · 96 citations · Full text

Life Sciences, Cancer Biology, Genetics +13

5′-Modifications improve potency and efficacy of DNA donors for precision genome editing

Krishna S. Ghanta, Zexiang Chen, Aamir Mir et al. · eLife · 2021 · 72 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins

Paradesi Naidu Gollavilli, Aishwarya Pawar, Kari Wilder-Romans et al. · Cancer Research · 2018 · 68 citations

Medicine, Cancer Biology, Oncology +17