Xiao Xiao Tang

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

Alejandro A. Pezzulo, Xiao Xiao Tang, Mark J. Hoegger et al. · Nature · 2012 · 797 citations · Full text

Lung Inflammation, Surface Ph, Pulmonary Physiology +8

Airway acidification initiates host defense abnormalities in cystic fibrosis mice

Viral S. Shah, David K. Meyerholz, Xiao Xiao Tang et al. · Science · 2016 · 291 citations · Full text

Acidic pH increases airway surface liquid viscosity in cystic fibrosis

Xiao Xiao Tang, Lynda S. Ostedgaard, Mark J. Hoegger et al. · Journal of Clinical Investigation · 2016 · 243 citations · Full text

Tracheobronchitis, Lung Inflammation, Respiratory Toxicology +12

Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia

Katrina Anne Muraglia, Rajeev Chorghade, Bo Ram Kim et al. · Nature · 2019 · 105 citations

Molecular Physiology, Small-molecule Ion Channels, Immunology +11

Relationships among CFTR expression, HCO ₃ ⁻ secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies

Viral S. Shah, Sarah E. Ernst, Xiao Xiao Tang et al. · Proceedings of the National Academy of Sciences · 2016 · 77 citations · Full text

Protein Secretion, Immune Regulation, Immunology +19