Concepedia

Norman E. Wideburg

NE

Statistics

Publications

19

Citations

1.9K

H-Index

16

Active since

1962

Affiliations

Abbott Fund(Current)

Abbott (United Kingdom)

Abbott (United States)

Norman E. Wideburg is an author at Abbott Fund specializing in enzyme inhibition, medicinal chemistry, and drug discovery.

Publications per year

1962–2003

19

Publications

19

Design, Activity, and 2.8 Å Crystal Structure of a <i>C</i> <sub>2</sub> Symmetric Inhibitor Complexed to HIV-1 Protease

John W. Erickson, David J. Neidhart, John H. VanDrie et al. · Science · 1990 · 528 citations · Full text

, , +17

Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor

David D. Ho, T. TOYOSHIMA, Hongmei Mo et al. · Journal of Virology · 1994 · 213 citations · Full text

, , +17

Structure-based, C2 symmetric inhibitors of HIV protease

Dale J. Kempf, Daniel W. Norbeck, LynnMarie Codacovi et al. · Journal of Medicinal Chemistry · 1990 · 211 citations · Full text

, , +13

Discovery of Ritonavir, a Potent Inhibitor of HIV Protease with High Oral Bioavailability and Clinical Efficacy

Dale J. Kempf, Hing L. Sham, Kennan C. Marsh et al. · Journal of Medicinal Chemistry · 1998 · 207 citations · Full text

, , +17

Influence of stereochemistry on activity and binding modes for C2 symmetry-based diol inhibitors of HIV-1 protease

M.V. Hosur, Talapady N. Bhat, Dale J. Kempf et al. · Journal of the American Chemical Society · 1994 · 133 citations

, , +16

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