Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

Erez Dror, Élise Dalmas, Daniel T. Meier, +17

Nature Immunology

InflammationMetabolic SyndromeCytokineInsulin SignalingInsulin Management +10

The Role of Inflammation in β-cell Dedifferentiation

Thierry M. Nordmann, Erez Dror, Friederike Schulze, +5

Scientific Reports

Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis

Shuyang Traub, Daniel T. Meier, Friederike Schulze, +11

Cell Reports

Metabolic SyndromeGlucose ToleranceInsulin SignalingMolecular PhysiologySignal Transduction +13

β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion

Marianne Böni‐Schnetzler, Stéphanie P. Häuselmann, Élise Dalmas, +10

Cell Reports

ImmunologyImmune Regulationβ Cell-specific DeletionInsulin SignalingImmune Dysregulation +20

Angiotensin II Induces Interleukin-1β–Mediated Islet Inflammation and β-Cell Dysfunction Independently of Vasoconstrictive Effects

Nadine S. Sauter, Constanze Thienel, Yuliya Plutino, +10

Diabetes

Immune RegulationImmunologyRenal InflammationGlucose ToleranceInsulin Signaling +21

Inhibition of the Hypoxia-Inducible Factor 1α–Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease

Peter Mirtschink, Corinne Bischof, Minh Duc Pham, +15

Circulation

Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing

Daniel T. Meier, Leila Rachid, Sophia J. Wiedemann, +11

Nature Communications

Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes

Friederike Schulze, Josua Wehner, Denise V. Kratschmar, +16

Scientific Reports