Tonia J. Buchholz

Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome

Susan D. Demo, Christopher J. Kirk, Monette Aujay et al. · Cancer Research · 2007 · 668 citations · Full text

Structural Basis for Binding Specificity between Subclasses of Modular Polyketide Synthase Docking Domains

Tonia J. Buchholz, Todd W. Geders, Frank E. Bartley et al. · ACS Chemical Biology · 2009 · 118 citations · Full text

Bioorganic Chemistry, Protein Assembly, Biomolecular Structure Prediction +18

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

Diego Acosta‐Alvear, Min Y. Cho, Thomas Wild et al. · eLife · 2015 · 99 citations · Full text

Immunology, Pathology, Paradoxical Resistance +20

Immunoproteasome functions explained by divergence in cleavage specificity and regulation

Michael B. Winter, Florencia La Greca, Shirin Arastu‐Kapur et al. · eLife · 2017 · 81 citations · Full text

Cleavage Specificity, Immunology, Immunodominance +21

In Vivo and In Vitro Trans-Acylation by BryP, the Putative Bryostatin Pathway Acyltransferase Derived from an Uncultured Marine Symbiont

Nicole B. Lopanik, Jennifer A. Shields, Tonia J. Buchholz et al. · Chemistry & Biology · 2008 · 76 citations · Full text

Biology, Biosynthesis, Marine Biotechnology +10