Ineta Kalniņa

Association of metformin administration with gut microbiome dysbiosis in healthy volunteers

Ilze Elbere, Ineta Kalniņa, Ivars Silamiķelis et al. · PLoS ONE · 2018 · 133 citations · Full text

Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients

Linda Tarāsova, Ineta Kalniņa, Kristine Geldnere et al. · Pharmacogenetics and Genomics · 2012 · 131 citations

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

Markus Sällman Almén, Emil Nilsson, Josefin A. Jacobsson et al. · Gene · 2014 · 93 citations · Full text

Obesity, Metabolic Syndrome, Methylation Change +15

Metformin Strongly Affects Gut Microbiome Composition in High-Fat Diet-Induced Type 2 Diabetes Mouse Model of Both Sexes

Laila Silamiķele, Ivars Silamiķelis, Monta Ustinova et al. · Frontiers in Endocrinology · 2021 · 56 citations · Full text

Both Sexes, Metformin Action, Dysbiosis +20

Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients

Ilze Elbere, Ivars Silamiķelis, Ilze Izabella Dindune et al. · PLoS ONE · 2020 · 55 citations · Full text