Osamu Okazaki

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

Miho Kazui, Yumi Nishiya, Tomoko Ishizuka et al. · Drug Metabolism and Disposition · 2009 · 808 citations

Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

Akinori Kimura, Haruhito Harada, Jeong-Euy Park et al. · Nature Genetics · 1997 · 572 citations

Cardiac Muscle, Cardiomyopathy, Medicine +8

Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation

Ken Okumura, Masaharu Akao, Tetsuro Yoshida et al. · New England Journal of Medicine · 2020 · 318 citations

Nighttime Blood Pressure Phenotype and Cardiovascular Prognosis

Kazuomi Kario, Satoshi Hoshide, Hiroyuki Mizuno et al. · Circulation · 2020 · 278 citations · Full text

A Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent Binding

Shintaro Nakayama, Ryo Atsumi, Hideo Takakusa et al. · Drug Metabolism and Disposition · 2009 · 246 citations

Drug Safety, Substance Abuse, Predictive Toxicology +8