Agustin Chicas

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber, Junwei Shi, Eric Wang et al. · Nature · 2011 · 1.9K citations

Hematological Malignancy, Hematology, Myeloid Neoplasia +7

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

Yuchen Chien, Claudio Scuoppo, Xiaowo Wang et al. · Genes & Development · 2011 · 956 citations · Full text

Aging, Immunology, Immune Regulation +19

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

William A. Freed-Pastor, Hideaki Mizuno, Xi Zhao et al. · Cell · 2012 · 850 citations · Full text

Medicine, Mevalonate Pathway, Mammary Gland +8

A Novel Role for High-Mobility Group A Proteins in Cellular Senescence and Heterochromatin Formation

Masashi Narita, Masako Narita, Valery Krizhanovsky et al. · Cell · 2006 · 604 citations · Full text

Chromatin, Chromatin Structure, Chromatin Remodeling +13

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

Nilgun Tasdemir, Ana Banito, Jae‐Seok Roe et al. · Cancer Discovery · 2016 · 385 citations · Full text