Differential SUMOylation of LXRα and LXRβ Mediates Transrepression of STAT1 Inflammatory Signaling in IFN-γ-Stimulated Brain Astrocytes

Jee Hoon Lee, Sang Myun Park, Ohn Soon Kim, +5

Molecular Cell

NeuroinflammationInflammationTranscriptional RegulationSignal TransductionSignaling Pathway +13

Microglial phagocytosis is enhanced by monomeric α‐synuclein, not aggregated α‐synuclein: Implications for Parkinson's disease

Ji Young Park, Seung R. Paik, Ilo Jou, +1

Glia

ImmunologyResident MacrophagesCell DeathNeurochemical BiomarkersNeuroinflammation +14

On the mechanism of internalization of α‐synuclein into microglia: roles of ganglioside GM1 and lipid raft

Ji Young Park, Kwang S. Kim, Saet-byul Lee, +6

Journal of Neurochemistry

LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Insup Choi, Beomsue Kim, Ji-Won Byun, +12

Nature Communications

Distinct Roles of the N-terminal-binding Domain and the C-terminal-solubilizing Domain of α-Synuclein, a Molecular Chaperone

Sang Myun Park, Han Young Jung, Thomas D. Kim, +3

Journal of Biological Chemistry

DJ-1 Associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes

Kwang S. Kim, Jin-Soo Kim, Ji Young Park, +4

Human Molecular Genetics

Proteinlipid InteractionNeurochemical BiomarkersLps-tlr4 SignalingSynaptic SignalingCellular Physiology +23

Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes

Jee Hoon Lee, Ji‐Hye Han, Hyunmi Kim, +3

Acta Neuropathologica Communications

Pink1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced akt and increased p38 mapk activation, and downregulation of egfr

Insup Choi, Jun Kim, Hey‐Kyeong Jeong, +7

Glia

Pink1 DeficiencyMitophagyPink1-ko AstrocytesDevelopmental BiologyMitochondrial Function +11

FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis

Yu Ree Choi, Seo-Jun Kang, Jin-Mo Kim, +4

Neurobiology of Disease

InflammationNeurodegenerative DiseasesMedicineImmune RegulationImmunology +10

DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression

Jin‐Mo Kim, Seon‐Heui Cha, Yu Ree Choi, +3

Scientific Reports