Hazel Lote

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 1.9K citations · Full text

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Khurum Khan, David Cunningham, Benjamin Werner et al. · Cancer Discovery · 2018 · 233 citations · Full text

Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study

Khurum Khan, Mihaela Rata, David Cunningham et al. · Gut · 2017 · 70 citations · Full text

KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer

Francesco Sclafani, Ian Chau, David Cunningham et al. · Scientific Reports · 2018 · 61 citations · Full text

miR-31-3p Expression and Benefit from Anti-EGFR Inhibitors in Metastatic Colorectal Cancer Patients Enrolled in the Prospective Phase II PROSPECT-C Trial

Gayathri Anandappa, Andrea Lampis, David Cunningham et al. · Clinical Cancer Research · 2019 · 45 citations · Full text