Sarah O’Keefe

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

Guanghui Zong, Zhijian Hu, Sarah O’Keefe et al. · Journal of the American Chemical Society · 2019 · 96 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +13

An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum

Sarah O’Keefe, Guanghui Zong, Kwabena B. Duah et al. · Communications Biology · 2021 · 72 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum

Igor Gamayun, Sarah O’Keefe, Tillman Pick et al. · Cell chemical biology · 2019 · 54 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Ipomoeassin-F inhibits the <i>in vitro</i> biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor

Sarah O’Keefe, Peristera Roboti, Kwabena B. Duah et al. · Journal of Cell Science · 2021 · 44 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Ring Expansion Leads to a More Potent Analogue of Ipomoeassin F

Guanghui Zong, Zhijian Hu, Kwabena B. Duah et al. · The Journal of Organic Chemistry · 2020 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13