Concepedia

Ring Expansion Leads to a More Potent Analogue of Ipomoeassin F

Guanghui Zong, Zhijian Hu, Kwabena B. Duah, Lauren Andrews, Jianhong Zhou, Sarah O’Keefe, Lucas Whisenhunt, Joong Sup Shim, Yuchun Du, Stephen High,

The Journal of Organic Chemistry · 2020 · 36 citations · 36 references

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Abstract

enabled gram-scale production, allowing us to establish that ipomoeassin F is biologically active in vivo (MTD: ∼3 mg/kg).

References

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