Molly A. McShea

Discovery and Optimization of HKT288, a Cadherin-6–Targeting ADC for the Treatment of Ovarian and Renal Cancers

Carl Uli Bialucha, Scott D. Collins, Xiao Li et al. · Cancer Discovery · 2017 · 52 citations · Full text

A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation

Nicholas C. Yoder, Chen Bai, Daniel Tavares et al. · Molecular Pharmaceutics · 2019 · 36 citations

Immunology, Pharmacotherapy, Lysine Conjugation +18

Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans

Molly A. McShea, Kristopher L. Schmidt, Michelle L. Dubuke et al. · Developmental Biology · 2012 · 23 citations · Full text

Signal Transduction, Guided Cell Migrations, Signaling Pathway +9

Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates

Kalli C. Catcott, Molly A. McShea, Carl Uli Bialucha et al. · mAbs · 2016 · 22 citations · Full text

Bioanalysis, Immunology, Maytansinoid Adcs +13

CD117-Amanitin Antibody Drug Conjugates Effectively Deplete Human and Non-Human Primate HSCs: Proof of Concept As a Targeted Strategy for Conditioning Patients for Bone Marrow Transplant

Bradley R. Pearse, Sean M. McDonough, Jennifer Proctor et al. · Blood · 2018 · 11 citations