Leena Otsomaa

<scp>ORM</scp>‐10103, a novel specific inhibitor of the <scp><scp>Na⁺/Ca²⁺</scp></scp> exchanger, decreases early and delayed afterdepolarizations in the canine heart

Norbert Jost, Norbert Nagy, Claudia Corici et al. · British Journal of Pharmacology · 2013 · 73 citations · Full text

Medicine, Cardiology, Pharmacology +17

The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments

Zsófia Kohajda, Nikolett Farkas‐Morvay, Norbert Jost et al. · PLoS ONE · 2016 · 64 citations · Full text

Medicine, Cardiology, Pharmacology +17

Long-Term Effects of Na+/Ca2+ Exchanger Inhibition with ORM-11035 Improves Cardiac Function and Remodelling without Lowering Blood Pressure in a Model of Heart Failure with Preserved Ejection Fraction

Uwe Primeßnig, T Bracic, Jouko Levijoki et al. · European Journal of Heart Failure · 2019 · 28 citations · Full text

Medicine, Cardiology, Pharmacology +15

Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity

Leena Otsomaa, Jouko Levijoki, Gerd Wohlfahrt et al. · British Journal of Pharmacology · 2020 · 15 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes

Kinga Oravecz, Anita Kormos, Andrea Grüber et al. · European Journal of Pharmacology · 2017 · 14 citations · Full text

Medicine, Pharmacology, Physiology +9