Gino Heeren

Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg, Heide Knauer, Alexandra Schauer et al. · Nature Cell Biology · 2009 · 1.6K citations · Full text

Lifespan Extension, Cell Autophagy, Mitophagy +6

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

Markus Ralser, Mirjam M. C. Wamelink, Axel Kowald et al. · Journal of Biology · 2007 · 605 citations · Full text

Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast

Mark Rinnerthaler, Sabrina Büttner, Peter Laun et al. · Proceedings of the National Academy of Sciences · 2012 · 144 citations · Full text

Genetics, Molecular Biology, Cell Death +25

Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span

Andreas G. Chiocchetti, Jia Zhou, Huashun Zhu et al. · Experimental Gerontology · 2006 · 121 citations

Medicine, Natural Sciences, Protein Biosynthesis +10

MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria

Mark Rinnerthaler, Stefanie Jarolim, Gino Heeren et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2006 · 103 citations

Tumor Biology, Medicine, Yeast Orthologue +9