David C. Linehan

Prevalence of Regulatory T Cells Is Increased in Peripheral Blood and Tumor Microenvironment of Patients with Pancreas or Breast Adenocarcinoma

Udaya Liyanage, Todd T. Moore, Hong‐Gu Joo et al. · The Journal of Immunology · 2002 · 1.5K citations

Life Sciences, Immunology, Oncology +13

CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

Yu Zhu, Brett L. Knolhoff, Melissa A. Meyer et al. · Cancer Research · 2014 · 1.3K citations · Full text

Medicine, Immunology, Oncology +17

Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff et al. · Cancer Research · 2012 · 941 citations

Medicine, Immunology, Oncology +15

Pretreatment Assessment of Resectable and Borderline Resectable Pancreatic Cancer: Expert Consensus Statement

Mark P. Callery, Kenneth J. Chang, Elliot K. Fishman et al. · Annals of Surgical Oncology · 2009 · 898 citations

Medicine, Oncology, Surgery +16

Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial

Timothy M. Nywening, Andrea Wang‐Gillam, Dominic E. Sanford et al. · The Lancet Oncology · 2016 · 778 citations · Full text

Medicine, Oncology, Pharmacology +16