Dominic E. Sanford

Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff et al. · Cancer Research · 2012 · 929 citations · Full text

Immunology, Biological Microenvironments, Immunoediting +20

Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial

Timothy M. Nywening, Andrea Wang‐Gillam, Dominic E. Sanford et al. · The Lancet Oncology · 2016 · 746 citations · Full text

Pancreatic Cancer, Tumour-associated Macrophages, Medicine +8

Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis

Dominic E. Sanford, Brian A. Belt, Roheena Z. Panni et al. · Clinical Cancer Research · 2013 · 597 citations · Full text

Targeting both tumour-associated CXCR2⁺ neutrophils and CCR2⁺ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma

Timothy M. Nywening, Brian A. Belt, Darren R. Cullinan et al. · Gut · 2017 · 465 citations · Full text

Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer

Roheena Z. Panni, Dominic E. Sanford, Brian A. Belt et al. · Cancer Immunology Immunotherapy · 2014 · 216 citations · Full text