Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS

D. Pilla, Jon A. Hagar, Arun Kumar Haldar, +7

Proceedings of the National Academy of Sciences

Microbial PathogensApoptosisImmunologyInnate Immune SystemMolecular Biology +26

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida

Étienne Meunier, Pierre Wallet, Roland F. Dreier, +12

Nature Immunology

Aim2 InflammasomeMicrobial PathogensVirulence FactorPathogenesisImmunology +7

<scp>LPS</scp> targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation

José Carlos Santos, Mathias S. Dick, Brice Lagrange, +7

The EMBO Journal

Protein SecretionBacterial Outer MembraneMicrobial PathogensMedicineNatural Sciences +8

Extensive Characterization of IFN-Induced GTPases mGBP1 to mGBP10 Involved in Host Defense

Daniel Degrandi, Carolin Konermann, Cornelia Beuter-Gunia, +5

The Journal of Immunology

ImmunologyIfn-induced Gtpases Mgbp1Immunologic MechanismInnate ImmunityExtensive Characterization +17

Murine Guanylate Binding Protein 2 (mGBP2) controls<i>Toxoplasma gondii</i>replication

Daniel Degrandi, Elisabeth Kravets, Carolin Konermann, +7

Proceedings of the National Academy of Sciences

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

Elizabeth M. Selleck, Sarah J. Fentress, Wandy L. Beatty, +5

PLoS Pathogens

The role of herpesvirus entry mediator as a negative regulator of T cell–mediated responses

Yang Wang, Sumit K. Subudhi, Robert A. Anders, +10

Journal of Clinical Investigation

Negative RegulatorAdaptive Immune SystemT-regulatory CellImmunologyImmunologic Mechanism +19

The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria

Daniel Degrandi, Reinhard Hoffmann, Cornelia Beuter-Gunia, +1

Journal of Interferon & Cytokine Research

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationIntracellular Pathogens +15

Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes

Elisabeth Kravets, Daniel Degrandi, Qijun Ma, +7

eLife

Toxoplasma Gondii ControlBiochemistryMurine GbpsNatural SciencesMolecular Biology +12

Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies

Alexandra Kresse, Carolin Konermann, Daniel Degrandi, +4

BMC Genomics