Brice Lagrange

Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms

Michal P. Wandel, Bae-Hoon Kim, Eui‐Soon Park et al. · Nature Immunology · 2020 · 276 citations · Full text

Guanylate-binding Proteins, Microbiology, Molecular Biology +1

<scp>LPS</scp> targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation

José Carlos Santos, Mathias S. Dick, Brice Lagrange et al. · The EMBO Journal · 2018 · 238 citations · Full text

Protein Secretion, Bacterial Outer Membrane, Microbial Pathogens +10

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11

Brice Lagrange, Sacha Benaoudia, Pierre Wallet et al. · Nature Communications · 2018 · 184 citations · Full text

Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia

Romain Aucagne, Nathalie Droin, Jérôme Paggetti et al. · Journal of Clinical Investigation · 2011 · 108 citations · Full text

Human Cmml, Cmml Patients, Immunology +20

NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

Tingting Niu, Charlotte de Rosny, Séverine Chautard et al. · Nature Communications · 2021 · 102 citations · Full text