Concepedia

Jacob M. Hughes

JM

Statistics

Publications

3

Citations

55

H-Index

3

Active since

2023

Affiliations

Uniformed Services University of the Health Sciences(Current)

University of Nebraska Medical Center

Jacob M. Hughes is an author at Uniformed Services University of the Health Sciences specializing in receptor tyrosine kinase oncogenes, therapeutic resistance, and mek inhibition.

ORCID

Publications per year

2023–2024

3

Publications

3

SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

Brianna R. Daley, Heidi M. Vieira, Chaitra Rao et al. · Proceedings of the National Academy of Sciences · 2023 · 28 citations · Full text

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In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies

Nancy E. Sealover, Patricia L. Theard, Jacob M. Hughes et al. · iScience · 2023 · 15 citations · Full text

, , +17

SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma

Brianna R. Daley, Nancy E. Sealover, Bridget A. Finniff et al. · Cancer Research · 2024 · 12 citations · Full text

, , +17

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