Alejandro Soto-Ospina

Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1I249/M280 Variant

Sandra M. Cardona, Sangwon V. Kim, Kaira A. Church et al. · Frontiers in Cellular Neuroscience · 2018 · 59 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Structural Protein Effects Underpinning Cognitive Developmental Delay of the PURA p.Phe233del Mutation Modelled by Artificial Intelligence and the Hybrid Quantum Mechanics–Molecular Mechanics Framework

Juan Javier López Rivera, Luna Rodríguez‐Salazar, Alejandro Soto-Ospina et al. · Brain Sciences · 2022 · 17 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer’s disease in a multigenerational Colombian Family

J Moreno, Andrés Villegas Lanau, Lucía Madrigal Zapata et al. · PLoS ONE · 2022 · 14 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations

Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel Bedoya et al. · Biochemistry Research International · 2021 · 12 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Diffusion Mechanism Modeling of Metformin in Human Organic Cationic Amino Acid Transporter one and Functional Impact of S189L, R206C, and G401S Mutation

Leydy Cano, Alejandro Soto-Ospina, Pedronel Araque Marín et al. · Frontiers in Pharmacology · 2021 · 10 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17