T. Gheyi

Crystal structure of the human PRMT5:MEP50 complex

Stephen Antonysamy, Zahid Bonday, Robert M. Campbell et al. · Proceedings of the National Academy of Sciences · 2012 · 363 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD⁺) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

Xun Zhao, Dagart Allison, Bradley Condon et al. · Journal of Medicinal Chemistry · 2013 · 216 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +12

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

Hannah Nguyen, Abdellah Allali‐Hassani, Stephen Antonysamy et al. · Journal of Biological Chemistry · 2015 · 131 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +11

Liver Fatty Acid-binding Protein Initiates Budding of Pre-chylomicron Transport Vesicles from Intestinal Endoplasmic Reticulum

Indira Neeli, Shadab A. Siddiqi, Shahzad Siddiqi et al. · Journal of Biological Chemistry · 2007 · 119 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant

S. Atwell, Christie G. Brouillette, K. Conners et al. · Protein Engineering Design and Selection · 2010 · 99 citations

Life Sciences, Biochemistry, Molecular Biology +14