T. Parry

Discovery, Synthesis, and <i>in Vivo</i> Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase

Andrew Mortlock, Kevin M. Foote, Nicola M. Heron et al. · Journal of Medicinal Chemistry · 2007 · 274 citations · Full text

Medicine, Oncology, Pharmacology +13

Evaluation of the pharmacodynamics and pharmacokinetics of the PARP inhibitor olaparib: a Phase I multicentre trial in patients scheduled for elective breast cancer surgery

Nigel Bundred, Jānis Gardovskis, Janusz Jaśkiewicz et al. · Investigational New Drugs · 2013 · 89 citations

Medicine, Pharmacokinetics, Pharmacology +12

A Comparison of the Quantitative Methods for the Analysis of the Platinum-Containing Anticancer Drug {<i>cis</i>-[Amminedichloro(2-methylpyridine)]- platinum(II)} (ZD0473) by HPLC Coupled to Either a Triple Quadrupole Mass Spectrometer or an Inductively Coupled Plasma Mass Spectrometer

Christopher J. Smith, Ian D. Wilson, Fadi R. Abou-Shakra et al. · Analytical Chemistry · 2003 · 40 citations

Pharmacy, Chemistry, Pharmaceutical Analysis +17

Metabolism by conjugation appears to confer resistance to paracetamol (acetaminophen) hepatotoxicity in the cynomolgus monkey

Hong Yu, Nigel Barrass, Sonya Gales et al. · Xenobiotica · 2014 · 17 citations

Pharmacy, Pharmacology, Toxicology +16