Wenjie Luo

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

Peng Yuan, Carlo Condello, C. Dirk Keene et al. · Neuron · 2016 · 760 citations · Full text

Alzheimer's Disease, Amyloid Compaction, Medicine +10

Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells

Ishaan Gupta, Paul Collier, Bettina Haase et al. · Nature Biotechnology · 2018 · 355 citations · Full text

Functional Genomics, Single Cell Sequencing, Medicine +12

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

Gen He, Wenjie Luo, Peng Li et al. · Nature · 2010 · 322 citations · Full text

Neurodegenerative Diseases, Signal Transduction, Alzheimer's Disease +8

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesús Madero‐Pérez, Danielle L. Swaney et al. · Cell · 2022 · 299 citations · Full text

Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

Chao Wang, Li Fan, Rabia R. Khawaja et al. · Nature Communications · 2022 · 284 citations · Full text