Transcriptome Analysis of Psoriasis in a Large Case–Control Sample: RNA-Seq Provides Insights into Disease Mechanisms

Bingshan Li, Lam C. Tsoi, William R. Swindell, +12

Journal of Investigative Dermatology

Transcriptome AnalysisGeneticsImmunologyRna SequencingGene Regulation +8

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis

Andrew Johnston, Xianying Xing, Liza Wolterink, +6

Journal of Allergy and Clinical Immunology

InflammationCytokineAutoimmune DiseaseGeneralized Pustular PsoriasisMedicine +5

IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression

Andrew Johnston, Xianying Xing, Andrew M. Guzman, +11

The Journal of Immunology

ImmunologyImmune RegulationNovel CytokinesInnate ImmunityDermatology +16

Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa

Mrinal K. Sarkar, Grace A. Hile, Lam C. Tsoi, +18

Annals of the Rheumatic Diseases

Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis

Feiyang Ma, Olesya Plazyo, Allison C. Billi, +25

Nature Communications

Genome-Wide Expression Profiling of Five Mouse Models Identifies Similarities and Differences with Human Psoriasis

William R. Swindell, Andrew Johnston, Steve Carbajal, +14

PLoS ONE

EngineeringGeneticsImmunologyGene CharacterizationGenomics +23

Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses

Lam C. Tsoi, Elke Rodríguez, Dora Stölzl, +20

Journal of Allergy and Clinical Immunology

InflammationAllergyCytokine ResponsesAtopic DermatitisAcute-to-chronic Atopic Dermatitis +8

Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis

Jóhann E. Guðjónsson, Lam C. Tsoi, Feiyang Ma, +30

JCI Insight

Tyrosine KinaseImmune RegulationImmunologySuppurativa PathogenesisImmunologic Mechanism +25

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

William R. Swindell, Kellie A. Michaels, Andrew J. Sutter, +7

Genome Medicine

IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus

Shuai Shao, Lam C. Tsoi, Mrinal K. Sarkar, +17

Science Translational Medicine