Claire Worrall

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

Huiyuan Zheng, Claire Worrall, Hongchang Shen et al. · Proceedings of the National Academy of Sciences · 2012 · 100 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

β-Arrestin–biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor–targeting antibodies in Ewing’s sarcoma

Huiyuan Zheng, Hongchang Shen, Iulian I. Oprea et al. · Proceedings of the National Academy of Sciences · 2012 · 65 citations · Full text

Medicine, Oncology, Pharmacology +16

Effect of Acid Suppression on Molecular Predictors for Esophageal Cancer

Pierre Lao‐Sirieix, Amanda Roy, Claire Worrall et al. · Cancer Epidemiology Biomarkers & Prevention · 2006 · 40 citations

Medicine, Oncology, Pharmacology +17

Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma

Claire Worrall, Naida Suleymanova, Caitrin Crudden et al. · Oncogene · 2017 · 36 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes

Naida Suleymanova, Caitrin Crudden, Takashi Shibano et al. · Oncogene · 2017 · 32 citations · Full text

Life Sciences, Molecular Biology, Oncology +17