Iulian I. Oprea

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

Samir EL Andaloussi, Taavi Lehto, Imre Mäger et al. · Nucleic Acids Research · 2011 · 296 citations · Full text

Engineering, Peptide Engineering, Immunology +22

β-Arrestin–biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor–targeting antibodies in Ewing’s sarcoma

Huiyuan Zheng, Hongchang Shen, Iulian I. Oprea et al. · Proceedings of the National Academy of Sciences · 2012 · 65 citations · Full text

Optimizing anti-gene oligonucleotide ‘Zorro-LNA’ for improved strand invasion into duplex DNA

Eman M. Zaghloul, Andreas S. Madsen, Pedro M. D. Moreno et al. · Nucleic Acids Research · 2010 · 34 citations · Full text

Bioorganic Chemistry, Chemical Composition, Genetics +20

Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes

Naida Suleymanova, Caitrin Crudden, Takashi Shibano et al. · Oncogene · 2017 · 32 citations · Full text

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

Pedro M. D. Moreno, Sylvain Geny, Y. Vladimir Pabon et al. · Nucleic Acids Research · 2013 · 30 citations · Full text

Engineering, Bis-locked Nucleic Acid, Lna Content +20