EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van Deun, Pieter Mestdagh, Patrizia Agostinis, +92

Nature Methods

Protein SecretionExtracellular MicrovesiclesTransparent ReportingOmicsIntracellular Trafficking +8

Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia

Isabel Van Audenhove, Majken Denert, Ciska Boucherie, +3

Journal of Biological Chemistry

Tissue EngineeringEngineeringCell AdhesionMolecular BiologyCytoskeleton +20

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization

Isabel Van Audenhove, Ciska Boucherie, Leen Pieters, +9

The FASEB Journal

Mapping cytoskeletal protein function in cells by means of nanobodies

Isabel Van Audenhove, Katrien Van Impe, David Ruano‐Gallego, +6

Cytoskeleton

Protein SecretionCytoskeletonAnalytical UltracentrifugationCellular PhysiologyCytoskeletal Protein Function +17

Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells

Isabel Van Audenhove, Nincy Debeuf, Ciska Boucherie, +1

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Cell SignalingCell AdhesionFascin Actin BundlingMolecular BiologyPodosome Turnover +8

Combination of interleukin-12 gene therapy, metronomic cyclophosphamide and DNA cancer vaccination directs all arms of the immune system towards tumor eradication

Sofie Denies, Laetitia Cicchelero, Isabel Van Audenhove, +1

Journal of Controlled Release

Immune EvasionCancer ImmunosurveillanceInterleukin-12 Gene TherapyMetronomic CyclophosphamideImmunology +11

A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles

Els Beghein, Isabel Van Audenhove, Olivier Zwaenepoel, +3

Scientific Reports

Inhibitory cortactin nanobodies delineate the role of NTA‐ and SH3‐domain–specific functions during invadopodium formation and cancer cell invasion

Laurence Bertier, Ciska Boucherie, Olivier Zwaenepoel, +4

The FASEB Journal

Nuclear fascin regulates cancer cell survival

Campbell D. Lawson, S Peel, Asier Jayo, +8

eLife

Histone H3Cell DeathMolecular BiologyCytoskeletonCancer Biology +17

VCA nanobodies target N-WASp to reduce invadopodium formation and functioning

Tim Hebbrecht, Isabel Van Audenhove, Olivier Zwaenepoel, +2

PLoS ONE

EngineeringMolecular BiologyCytoskeletonTumor BiologyCell Interaction +16