Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

Oleg V. Evgrafov, Irina Mersiyanova, Joy Irobi, +21

Nature Genetics

Neurodegenerative DiseasesNeurological DisorderMedicinePathologyDegenerative Disease +5

Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy

Joy Irobi, Katrien Van Impe, Pavel Seeman, +20

Nature Genetics

Peripheral NervesProtein FoldingMedicineExperimental NeuropathologyHot-spot Residue +4

A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis

Katrien Van Impe, Jonas Bethuyne, Steven K. Cool, +15

Breast Cancer Research

Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro

Anske Van den Abbeele, Veerle De Corte, Katrien Van Impe, +5

Cancer Letters

Tumor BiologyMedicineCancer GrowthCell-matrix InteractionTumor Suppressor +8

Increased importin-β-dependent nuclear import of the actin modulating protein CapG promotes cell invasion

Veerle De Corte, Katrien Van Impe, Erik Bruyneel, +4

Journal of Cell Science

CytoskeletonNuclear Export SequenceCancer BiologyImportin-β-dependent Nuclear ImportCellular Physiology +18

The Nucleo-cytoplasmic Actin-binding Protein CapG Lacks a Nuclear Export Sequence Present in Structurally Related Proteins

Katrien Van Impe, Veerle De Corte, Ludwig Eichinger, +4

Journal of Biological Chemistry

Structurally Related ProteinsMolecular BiologyCytoskeletonNuclear Export SequenceCellular Physiology +16

Mapping cytoskeletal protein function in cells by means of nanobodies

Isabel Van Audenhove, Katrien Van Impe, David Ruano‐Gallego, +6

Cytoskeleton

Protein SecretionCytoskeletonAnalytical UltracentrifugationCellular PhysiologyCytoskeletal Protein Function +17

A New Role for Nuclear Transport Factor 2 and Ran: Nuclear Import of CapG

Katrien Van Impe, Thomas Hubert, Veerle De Corte, +4

Traffic

The actin-capping protein CapG localizes to microtubule-dependent organelles during the cell cycle

Thomas Hubert, Katrien Van Impe, Joël Vandekerckhove, +1

Biochemical and Biophysical Research Communications

Actin-capping Protein CapgCell DivisionIntracellular TransportNatural SciencesMolecular Biology +9

A monopartite nuclear localization sequence regulates nuclear targeting of the actin binding protein myopodin

Ariane De Ganck, Thomas Hubert, Katrien Van Impe, +4

FEBS Letters