Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

Niccolò Bolli, Giulia Biancon, Matahi Moarii, +24

Leukemia

m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

Yimeng Gao, Radovan Vasic, Yuanbin Song, +22

Immunity

ImmunogeneticsDevelopmental BiologyLymphocyte DevelopmentInnate Immune SystemImmunology +7

Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma

Bachisio Ziccheddu, Giulia Biancon, Filippo Bagnoli, +17

Blood Advances

Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies

Giulia Biancon, Poorval Joshi, Joshua T. Zimmer, +20

Molecular Cell

Hematological MalignancyMedicinePrecision AnalysisMyeloid MalignanciesCancer Genomics +8

Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis

Hasan Halit Öz, Ee-chun Cheng, Caterina Di Pietro, +13

Cell Reports

Noninvasive Molecular Monitoring in Multiple Myeloma Patients Using Cell-Free Tumor DNA

Giulia Biancon, Silvia Gimondi, Antonio Vendramin, +2

Journal of Molecular Diagnostics

Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal

Eliezra Glasser, Debanjana Maji, Giulia Biancon, +7

Nucleic Acids Research

ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

Yimeng Gao, Joshua T. Zimmer, Radovan Vasic, +18

Cell Reports

Combined liver–cytokine humanization comes to the rescue of circulating human red blood cells

Yuanbin Song, Liang Shan, Rana Gbyli, +20

Science

In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2

Rana Gbyli, Yuanbin Song, Wei Liu, +14

Leukemia

Mutant Idh1/2Parp InhibitionChemoprevention StrategyMedicineAnti-cancer Agent +6