Doreen Dobritzsch

High Resolution Crystal Structure of Pyruvate Decarboxylase from Zymomonas mobilis

Doreen Dobritzsch, Stephan König, G. Schneider et al. · Journal of Biological Chemistry · 1998 · 172 citations · Full text

Life Sciences, Biochemistry, Microbiology +14

Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti‐cancer drug 5‐fluorouracil

Doreen Dobritzsch · The EMBO Journal · 2001 · 138 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12

Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity

André B. P. Kuilenburg, Judith Meijer, Adri N. Mul et al. · Human Genetics · 2010 · 113 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure

André B. P. Kuilenburg, Doreen Dobritzsch, Rutger Meinsma et al. · Biochemical Journal · 2002 · 111 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme

Doreen Dobritzsch, Huaming Wang, G. Schneider et al. · Biochemical Journal · 2014 · 108 citations

Life Sciences, Biochemistry, Microbiology +17