Arjan Lakeman

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

Jan J. Molenaar, Jan Köster, Danny A. Zwijnenburg et al. · Nature · 2012 · 870 citations · Full text

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

Marcel Kool, Jan Köster, Jens Bunt et al. · PLoS ONE · 2008 · 723 citations · Full text

Neuroblastoma is composed of two super-enhancer-associated differentiation states

Tim van Groningen, Jan Köster, Linda J. Valentijn et al. · Nature Genetics · 2017 · 554 citations

Neuro-oncology, Super-enhancer-associated Differentiation States, Developmental Biology +4

NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome

Michael Hölzel, Sidong Huang, Jan Köster et al. · Cell · 2010 · 221 citations · Full text

Tumor Biology, Disease Outcome, Medicine +7

A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma

Tim van Groningen, Nurdan Akogul, Ellen M. Westerhout et al. · Nature Communications · 2019 · 170 citations · Full text