Tim van Groningen

Neuroblastoma is composed of two super-enhancer-associated differentiation states

Tim van Groningen, Jan Köster, Linda J. Valentijn et al. · Nature Genetics · 2017 · 554 citations

Neuro-oncology, Super-enhancer-associated Differentiation States, Developmental Biology +4

A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma

Tim van Groningen, Nurdan Akogul, Ellen M. Westerhout et al. · Nature Communications · 2019 · 170 citations · Full text

A NOTCH3 Transcriptional Module Induces Cell Motility in Neuroblastoma

Johan van Nes, Alvin Chan, Tim van Groningen et al. · Clinical Cancer Research · 2013 · 54 citations · Full text

Mesenchymal Neuroblastoma Cells Are Undetected by Current mRNA Marker Panels: The Development of a Specific Neuroblastoma Mesenchymal Minimal Residual Disease Panel

Esther M. van Wezel, Lieke M. J. van Zogchel, Jalenka van Wijk et al. · JCO Precision Oncology · 2019 · 36 citations · Full text

Cell Therapy, Immunology, Pathology +20

Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma

Eirini Christodoulou, Mamunur Rashid, Clare Pacini et al. · Pigment Cell & Melanoma Research · 2020 · 27 citations · Full text

Melanoma Cell Lines, Tumor Biology, Genetic Dependencies +13