Shachar Raz

Chemotherapeutic Drug-Induced ABCG2 Promoter Demethylation as a Novel Mechanism of Acquired Multidrug Resistance

Eran Bram, Michal Stark, Shachar Raz et al. · Neoplasia · 2009 · 116 citations · Full text

Pharmacotherapy, Antimicrobial Chemotherapy, Antibiotic Resistance +22

Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability

Won Dong Lee, Anna Chiara Pirona, Boris Sarvin et al. · Cell Metabolism · 2020 · 68 citations

Tumor Biology, Radiation Oncology, Oncology +8

Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest

Shachar Raz, Daoud Sheban, Nitzan Gonen et al. · Cell Death and Disease · 2014 · 63 citations · Full text

Carcinoma Cells, Severe Hypoxia, Tumor Biology +17

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz, Shachar Raz, Michal Stark et al. · International Journal of Cancer · 2015 · 54 citations · Full text

Mixed-phenotype Acute Leukemia, Mediate Chemoresistance, Fpgs Function +17

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia

Shachar Raz, Michal Stark, Yehuda G. Assaraf · Oncotarget · 2014 · 13 citations · Full text