Shachar Raz

Chemotherapeutic Drug-Induced ABCG2 Promoter Demethylation as a Novel Mechanism of Acquired Multidrug Resistance

Eran Bram, Michal Stark, Shachar Raz et al. · Neoplasia · 2009 · 117 citations · Full text

Medicine, Oncology, Pharmacology +13

Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability

Won Dong Lee, Anna Chiara Pirona, Boris Sarvin et al. · Cell Metabolism · 2020 · 73 citations

Medicine, Cancer Biology, Oncology +16

Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest

Shachar Raz, Daoud Sheban, Nitzan Gonen et al. · Cell Death and Disease · 2014 · 64 citations · Full text

Medicine, Oncology, Pharmacology +17

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Anna Wojtuszkiewicz, Shachar Raz, Michal Stark et al. · International Journal of Cancer · 2015 · 55 citations · Full text

Medicine, Molecular Biology, Oncology +13

Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia

Shachar Raz, Michal Stark, Yehuda G. Assaraf · Oncotarget · 2014 · 13 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13