Peter O’Brien

Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease

A. Douangamath, D. Fearon, Paul Gehrtz et al. · Nature Communications · 2020 · 527 citations · Full text

Sharpless Asymmetric Aminohydroxylation: Scope, Limitations, and Use in Synthesis

Peter O’Brien · Angewandte Chemie International Edition · 1999 · 316 citations

A Readily-Accessible (+)-Sparteine Surrogate

Michael J. Dearden, Catherine R. Firkin, Jean‐Paul R. Hermet et al. · Journal of the American Chemical Society · 2002 · 244 citations

Recent advances in asymmetric synthesis using chiral lithium amide bases

Peter O’Brien · Journal of the Chemical Society Perkin Transactions 1 · 1998 · 238 citations

Chemical Engineering, Enantioselective Synthesis, Engineering +13

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

M. Schuller, G.J. Correy, Stefan Gahbauer et al. · Science Advances · 2021 · 198 citations · Full text

Engineering, Nsp3 Macrodomain, Molecular Biology +16