Eian Caulder

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

Alfonso Quintás‐Cardama, Kris Vaddi, Phillip Liu et al. · Blood · 2010 · 827 citations

Medicine, Hematology, Pharmacology +11

Selective Inhibition of ADAM Metalloproteases as a Novel Approach for Modulating ErbB Pathways in Cancer

Jordan S. Fridman, Eian Caulder, Michael Hansbury et al. · Clinical Cancer Research · 2007 · 144 citations · Full text

Medicine, Oncology, Pharmacology +9

Synergistic Inhibition with a Dual Epidermal Growth Factor Receptor/HER-2/neu Tyrosine Kinase Inhibitor and a Disintegrin and Metalloprotease Inhibitor

Lois Witters, Peggy Scherle, Steven Friedman et al. · Cancer Research · 2008 · 116 citations

Medicine, Oncology, Pharmacology +12

INCB16562, a JAK1/2 Selective Inhibitor, Is Efficacious against Multiple Myeloma Cells and Reverses the Protective Effects of Cytokine and Stromal Cell Support

Jun Li, Margaret Favata, Jennifer Kelley et al. · Neoplasia · 2010 · 79 citations · Full text

Medicine, Oncology, Pharmacology +16

Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells<i>in vitro</i>and<i>in vivo</i>

Renate Burger, Steven Le Gouill, Yu-Tzu Tai et al. · Molecular Cancer Therapeutics · 2009 · 60 citations · Full text

Medicine, Cell Biology, Pharmacology +16